Jose Mourinho is looking to avoid equalling his longest Premier League win-less run of five matches set at Chelsea from April to May 2007 and at Manchester United from April to May 2017.
Despite a promising start to his tenure, Spurs have been inconsistent under Mourinho in recent weeks, having won just one of their last five Premier League matches.
However,"Special one" will be hoping his side will get back to their winning ways against a rock bottom Norwich, who narrowly defeated Bournemouth in Carrow Road.
Midfielder Tanguy Ndombele has recovered from the hip injury he suffered on New Year's Day but Mourinho remains without Ben Davies, Harry Kane, Hugo Lloris and Moussa Sissoko.
Norwich defender Ben Godfrey is suspended following his sending off against Bournemouth.
Emiliano Buendia has been ruled out with a muscle problem and joins Timm Klose, Mario Vrancic and Ralf Fahrmann on the sidelines.
Bournemouth 3-1 Brighton.
Aston Villa 2-1 Watford.
Crystal Palace 0-2 Southampton.
Everton 2-2 Newcastle.
Sheffield United 0-1 Manchester City.
Chelsea 2-2 Arsenal.
Leicester City vs. West Ham United.
Tottenham Hotspur vs. Norwich City.
Manchester United vs. Burnley.
Wolverhampton Wanderers vs. Liverpool.