Sundowns completed a club record run in the group stages with a 1-0 win over Wydad Casablanca in Atteridgeville. Ricardo Nascimento scored the decisive goal in first-half stoppage time.
Mamelodi Sundowns and TP Mazembe will head into the 2019-20 Total CAF Champions League knockout stages as two of the favourites to clinch the crown after ending the group-stage campaign with an unbeaten record.
Both teams finished on 14 points with four wins and two draws from their allotted fixtures in Group A and C respectively.
Mazembe were also made to work for all three points, but ultimately claimed a comfortable 3-1 win over Zesco United in Lubumbashi.
FULL LIST OF RESULTS:
Mamelodi Sundowns 1-0 Wydad Casablanca.
TP Mazembe 3-1 ZESCO United.
Primeiro de Agosto 0-0 Zamalek.
USM Alger 2-2 Petro Atletico.