Nadal was the early aggressor as he choked Djokovic to win the opening set in brutal fashion having made only two unforced errors. He then kept a firm grip on a subdued Djokovic in the second set under the roof of court Philippe Chatrier.
Rafael Nadal claimed the 13th Roland Garros crown, beating Novak Djokovic 6-0, 6-2, 7-5 in two hours and 41 minutes.
Thus, the Spaniard equaled Roger Federer's record of 20 Major titles, securing his title of the greatest clay-courter once again and extending the reign in Paris after winning 100 matches from 102 encounters.
First of all of course congrats to Novak for another great tournament, sorry for today," Nadal, who has now beaten Djokovic in all of their three French Open finals, said on court.
"In Australia (in the final in 2019) he killed me. We've played so many times, one day one wins, another day the other wins."
Djokovic, who was looking to win his 18th Grand Slam title, rebelled in the third set, breaking back for 3-3, only to drop serve on a double fault in the 11th game before Nadal went on to bag his 100th victory at Roland Garros with an ace.
The Serbian had won five Grand Slam finals in a row since being beaten by Stan Wawrinka at the 2016 Australian Open, but Nadal was not upset on his turf despite a new stadium design, the roof and the lack of spectators amid the Covid-19 crisis.
The 34-year-old Nadal would not think of matching Federer's mark.
"To win here means everything. I don't think today about the 20th and equal Roger on this great number, today is just a Roland Garros victory and that means everything to me," the world number two said.
"This love story I have with this city and this court is unforgettable."
Meanwhile French tennis federation president Bernard Giudicelli says there are no plans to move the 2021 Roland Garros tournament from its traditional May-June slot after this year's event was shifted to the autumn due to the coronavirus pandemic.
The French Open was postponed by four months after the tennis season was put on hold due to the global health crisis.
Only 1 000 fans have been allowed to attend the Roland Garros grounds each day over the past two weeks, with Covid-19 cases on the rise again in France.
However, Giudicelli said on Sunday it was impossible to predict whether next year's edition would also be affected by the pandemic.
Timea Babos and Kristina Mladenovic enjoyed some sweet revenge following their US Open heartbreak as they retained their French Open doubles title to claim their fourth Grand Slam as a pair on Sunday.
Hungary's Babos and local favourite Kristina Mladenovic, who were withdrawn from the US Open due to Covid-19 protocols, have now won four of the last 11 women's majors with a 6-4 7-5 victory against Desirae Krawczyk and Alexa Guarachi in the Roland Garros final.
Mladenovic and Babos were withdrawn from the tournament ahead of the second round at Flushing Meadows after the Frenchwoman had to stay in quarantine in her hotel room following a game of cards with Benoit Paire, who tested positive for Covid-19.