Kick-off is at 6pm CAT (SA, GMT+2).
There has been conflicting reports with some saying the match will kick off at 16h00.
However, in an official correspondence to both SAFA and the Sudan Football Federation, CAF confirmed that the match to take place at Khartoum International Stadium will start at 18h00.
Bafana Bafana head into the clash in Omdurman in second spot in Group C, level on 10 points with already qualified Ghana, who close off their 2021 Afcon qualifying campaign at home to bottom-placed Sao Tome and Principe.
Sudan sit a point back and need a win this weekend to advance to next year's finals in Cameroon at South Africa's expense. A draw will be enough for Bafana Bafana to punch their Afcon ticket.
Bafana Bafana head coach Molefi Ntseki says his team have a plan for whatever Sudan offers on Sunday, knowing all too well that Hubert Velud's troops need to go all out for victory.
"In football, there's something very interesting, if you look we had more possession, very good opportunities but unfortunately we ended up with a draw and I think going to Sudan it's for them to lose," Ntseki said following Thursday's 1-1 draw against the Black Stars at FNB Stadium.
"Because they will be coming at us and we already have a plan for that, they have to play to win, a draw is not going to help them.
"So in this case they will have to come at us and coming at us, we have very good players who can play on the transition and get us a win."
While bemoaning some missed chances in the 1-1 draw with Ghana’s Black Stars on Thursday, 25 March 2021 at FNB Stadium, Ntseki said South Africa still had the destiny to qualify for Cameroon in their own hands.
The Falcons of Jediane have already caused an upset in the group stages, beating Ghana 1-0 in Omdurman last year and they defeated Sao Tome and Principe 2-0 on Wednesday to keep their Afcon hopes alive. All that bodes well for Sudan.
In head-to-head stats, South Africa boast a 100% record against Sudan, having beaten them twice enroute to qualifying for the 2015 Africa Cup of Nations tournament and 1-0 in the reverse fixture in November 2019. Lebogang Phiri scored the decisive goal at Orlando Stadium.
The top two nations in each group advance to the 24-team finals hosted in Cameroon next year.
Meanwhile, the entire travelling Bafana Bafana team and support staff have all been cleared after the latest Covid-19 results all came negative.
"We just received the team’s Covid-19 results and they are 100 percent clear. Everyone in camp tested negative," said Dr Ngwenya.