Buckingham Palace announced more details of their trip, revealing the parents would fly with baby Archie to Cape Town on the 23rd of September 2019.
And after a number of public appearances together, Meghan, 38, is expected to stay in Johannesburg with Archie while Prince Harry, 34, goes to Botswana, Angola and Malawi.
Announcing the tour, the palace said: "This will be Their Royal Highnesses' first official tour as a family."
The first day of the tour will begin in a township in Cape Town where Their Royal Highnesses will view a workshop that teaches children about their rights, self-awareness and safety and which provides self-defence classes and female empowerment training to young girls in the community.
They will conclude the day by attending a Reception at the British High Commissioner’s Residence, where they will meet inspiring opinion former's and young future leaders, underlining the rich and diverse nature of the UK’s modern partnership with South Africa.
On day three of the visit, Wednesday 25 September, The Duke and Duchess will meet Archbishop Desmond Tutu and Mrs Tutu at their legacy foundation. The Duke last met Archbishop Tutu in 2015, when he presented him with an honour in recognition of his services to UK communities and international peace and reconciliation.